In vitro models
Corneal Inflammation
Conjunctival Inflammation
Corneal Oxidative Stress
Conjunctival Oxidative Stress
Corneal Wound Healing
Corneal Apoptosis and Inflammation
Conjunctival Apoptosis and Inflammation
3D and Ex vivo Models
3D Modelof Human Conjunctiva
Ex vivo Culture of PorcineOcular Surface
In vivo Models
Corneal Epithelial Wound Healing Model
Partial Limbal Stem Cell Deficiency Model
Total Limbal Stem Cell Deficiency Mode
Assays in Cell Monolayer
Cell Viability
Cell Proliferation
Permeability
Intracellular Location
Transepithelial Resistance(TER)
Scratch Assay
Protein/mRNA Expression
Assays in 3D & Ex vivo Models
Tolerability
Permeability
Tissue Location
Wound Healing
Protein/mRNA Expression
Functional Assays(efficacy)
Assays in In vivo Models
Tolerability
WoundHealing
Histopathology
Protein/mRNA Expression
Good Laboratory Practices (GLP)
2.1. In vivo toxicity:
2.1.1. Short-term
2.1.2. Long-term
2.2. In vitro toxicity
2.4. Tolerance:
2.4.2. Ocular tolerance
9.5. Safety Pharmacology
9.9. Biocompatibility of medical devices