THE SCIENCE BEHIND IOBA CYTOTEST.
RELEVANT PUBLICATIONS

Acute retinal damage after using a toxic perfluoro-octane for vitreo-retinal surgery. Pastor JC, Coco RM, Fernandez-Bueno I, Alonso-Alonso ML, Medina J, Sanz-Arranz A, Rull F, Gayoso MJ, Dueñas A, Garcia-Gutierrez MT, Gonzalez-Buendia L, Delgado-Tirado S, Abecia E, Ruiz-Miguel M, Serrano MA, Ruiz-Moreno JM, Srivastava GK. Retina 2017;37:1140-1151.

The acute toxicity problem with some perfluorooctanes. Pastor Jimeno JC, Coco Martin RM. Arch Soc Esp Oftalmol 2017;92:455-457.

Comparison between direct contact and extract exposure methods for PFO cytotoxicity evaluation. Srivastava GK, Alonso-Alonso ML, Fernandez-Bueno I, Garcia-Gutierrez MT, Rull F, Medina J, Coco RM, Pastor JC. Sci Rep. 2018 23;8:1425.

Retinal Toxicity of Medical Devices Used during Vitreoretinal Surgery: A Critical Overview. Januschowski K, Irigoyen C, Pastor JC, Srivastava GK, Romano MR, Heimann H, Stalmans P, Van Keer K, Boden K, Szurman P, Spitzer MS. Ophthalmologica 2018;240:236-243.

Acute retinal toxicity associated with a mixture of perfluorooctane and perfluorohexyloctane: failure of another indirect cytotoxicity analysis. Coco RM, Srivastava GK, Andrés-Iglesias C, Medina J, Rull F, Fernandez-Vega-Gonzalez A, Fernandez-Bueno I, Dueñas A, Pastor JC. Br J Ophthalmol 2019;103:49-54.

Research related to clinical pictures of acute toxicity and toxic subtances identified in some lots of PFCL was presented in the last ARVO meeting in Vancounver (28th April – 2th May 2019):
- - Clinical characteristics of proven acute intraocular toxicity by perfluorocarbon liquids (PFCL) used in retinal surgery. Pastor JC, Andrés-Iglesias C, Srivastava GK, Fernández-Bueno I, Dueñas-Laita A, Rull F, Medina J, García-Serna J, Alfredo Garcia-Layana A, Coco-Martin R. Investigative Ophthalmology & Visual Science 2019;60:6597.
  - Cytotoxicity evaluation of toxic substances identified in recent reported toxic lots of perfluorocarbon liquids used in intraocular surgery in patients. Srivastava GK, Andrés-Iglesias C, Coco-Martin R, Fernández-Bueno I, Medina J, García-Serna J, Dueñas-Laita A, Rull F, Pastor JC. Investigative Ophthalmology & Visual Science 2019;60:6611.

Chemical compounds causing severe acute toxicity in heavy liquids used for intraocular surgery. Srivastava GK, Andrés-Iglesias C, Coco RM, Fernández-Bueno I, Medina J, García-Serna J, Dueñas A, Rull F, Pastor JC. Regul Toxicol Pharmacol 2019;110:104527.

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